Endocrine Abstracts

Metabolic syndrome and insulin resistance persist 5 years after remission of Cushing’s syndrome (CS). Adiponectin and visfatin are two adipokines highly expressed in adipose tissue. Adiponectin is reduced in obesity and insulin-resistant states; visfatin has been shown in some studies to be reduced in obesity. The aim was to evaluate visfatin and adiponectin levels, body composition, insulin resistance and prevalence of metabolic syndrome in a cohort of women with long-te...

High dose and long-term glucocorticoid (GC) therapy reduce bone mass and negatively affect the metabolic profile. Patients in remission after successful treatment of Cushing’s syndrome (CS) often present hypoadrenalism and require long-term GC replacement.Objective: To evaluate the effect of GC therapy on bone and metabolic parameters in women after long-term remission of CS. Materials and methods: Thirty-two women (mean age: 50±14 years) with ...